C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 209/30 (2006.01) A61K 31/403 (2006.01) A61K 31/404 (2006.01) A61K 31/416 (2006.01) A61P 25/28 (2006.01) C07D 209/08 (2006.01) C07D 209/42 (2006.01) C07D 209/86 (2006.01) C07D 231/56 (2006.01) C07D 401/04 (2006.01) C07D 405/04 (2006.01)
Patent
CA 2628934
Tetrahydroindole derivatives of formula (I): are disclosed. These compounds modulate the activity of gamma-secretase and hence find use in treatment or prevention of Alzheimer's disease.
La présente invention a pour objet des dérivés de tétrahydroindole de formule (I) : . Ces composés modulent l'activité de la gamma-secrétase, et trouvent donc une application dans le traitement prophylactique ou thérapeutique de la maladie d'Alzheimer.
Burkamp Frank
Checksfield Graham David
Fletcher Stephen Robert
Lewis Stephen John
Mciver Edward Giles
Merck Sharp & Dohme Limited
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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