C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 231/56 (2006.01) A61K 31/416 (2006.01) A61P 35/00 (2006.01) C07D 209/14 (2006.01)
Patent
CA 2598993
Disclosed are compounds and pharmaceutically acceptable salts of Formula (I): wherein R1, R2, R3, R4, R5, R6, R7, n, Q1, Q2, Q3, Y, and X1-X4 are as defined herein. Compounds of Formula (I) are useful in the treatment of diseases and/or conditions related to cell proliferation, such as cancer, inflammation, arthritis, angiogenesis, or the like. Also disclosed are pharmaceutical compositions comprising compounds of the invention and methods of treating the aforementioned conditions using such compounds .
La présente invention concerne des composés et des sels pharmaceutiquement acceptables de formule (I) : dans laquelle R1, R2, R3, R4, R5, R6, R7, n, Q1, Q2, Q3, Y, et X1 à X4 sont tels que définis ici. Les composés de formule (I) sont utiles dans le traitement des maladies et /ou des conditions liées à la prolifération cellulaire telles que le cancer, l~inflammation, l~arthrite, l~angiogenèse, ou similaire. Des compositions pharmaceutiques comprenant des composés de l~invention et des procédés de traitement des conditions sus-mentionnées utilisant de tels composés sont décrits.
Barta Thomas
Eaves Jeron
Geng Lifeng
Hanson Gunnar
Hinkley Lindsay
Osler Hoskin & Harcourt Llp
Serenex Inc.
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