Tetrahydroisoquinolines, pharmaceutical compositions...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 217/18 (2006.01) A61K 31/472 (2006.01) A61P 25/28 (2006.01) C07D 401/06 (2006.01) C07D 401/12 (2006.01) C07D 409/14 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01) C07D 498/04 (2006.01) C07D 513/04 (2006.01)

Patent

CA 2720004

The present invention relates to tetrahydroisoquinoline of the formula (I) or a physiologically tolerated salt thereof. The invention relates to pharmaceutical compositions comprising such tetrahydroisoquinolines, and the use of such tetrahydroiso-quinolines for therapeutic purposes. The tetrahydroisoquinolines are GIyT1 inhibitors.

La présente invention concerne la tétrahydroisoquinoléine représentée par la formule (I) ou un sel physiologiquement toléré de celle-ci. Linvention concerne des compositions pharmaceutiques comprenant de telles tétrahydroisoquinoléines et lutilisation de telles tétrahydroisoquinoléines à des fins thérapeutiques. Les tétrahydroisoquinoléines sont des inhibiteurs de GIyT1.

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