Tetrahydroisoquinolinylcarbamates of 1,2,3,3a,8,8a-...

Details Tetrahydroisoquinolinylcarbamates of 1,2,3,3a,8,8a-... Tetrahydroisoquinolinylcarbamates of 1,2,3,3a,8,8a-...

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/47 (2006.01)

Patent

CA 2085216

There are disclosed tetrahydroisoquinolinylcarbamates of 1,2,3,3a,8,8a- hexahydro-1,3a,8-trimethylpyrrolo[2,3-b]indole of formula (I), where R is hydrogen or loweralkyl; and X is hydrogen, loweralkyl, halogen, loweralkoxy or hydroxy, which compounds being useful for alleviating memory dysfunctions characterized by a cholinergic deficit.

On décrit des tétrahydroisoquinolinylcarbamates de 1,2,3,3a,8,8a-hexahydro-1,3a,8-triméthylpyrrolo[2,3-b]indole de la formule (I), où R représente hydrogène ou alkyle inférieur; et X représente hydrogène, alkyle inférieur, halogène, alcoxy inférieur ou hydroxyle. Ces composés sont utiles au soulagement de troubles de la mémoire caractérisés par un déficit cholinergique.

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