C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 39/42 (2006.01) A61K 31/055 (2006.01) A61K 31/09 (2006.01) A61K 31/222 (2006.01) A61K 31/277 (2006.01) A61P 25/00 (2006.01) A61P 31/08 (2006.01) A61P 35/00 (2006.01) C07C 39/17 (2006.01) C07C 43/21 (2006.01) C07C 43/225 (2006.01) C07C 43/23 (2006.01) C07C 69/157 (2006.01) C07C 255/54 (2006.01) C07C 255/55 (2006.01)
Patent
CA 2748963
The present invention relates to novel tetrahydronaphthalen-2-ol derivatives, to pharmaceutical compositions comprising these compounds and to their use in therapy, in particular to their use for the manufacture of a medicament for the prevention or treatment of lower urinary tract symptoms,benign prostate hyperplasia,prostate cancer,hot flushes, anxiety, depression, breast cancer, medullary thyroid carcinoma, ovarian cancer, inflammatory bowel disease, arthritis, endometriosis, and colon cancer.
La présente invention concerne de nouveaux dérivés du tétrahydronaphthalèn-2-ol, des compositions pharmaceutiques comprenant ces composés et leur utilisation en thérapie, L'invention concerne en particulier leur utilisation dans la fabrication d'un médicament pour la prévention ou le traitement de symptômes liés au tractus urinaire inférieur,de l'hyperplasie bénigne de la prostate, du cancer de la prostate, des bouffées de chaleur, de l'anxiété, de la dépression, du cancer du sein, du carcinome médullaire de la thyroïde, du cancer de l'ovaire, d'une maladie inflammatoire de l'intestin, de l'arthrite, de l'endométriose, et du cancer du colon.
Stock Herman Thijs
Teerhuis Neeltje Miranda
Veeneman Gerrit Herman
Fetherstonhaugh & Co.
N.v. Organon
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