C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/04 (2006.01) A61K 31/4745 (2006.01) A61K 31/4985 (2006.01) A61K 31/52 (2006.01) A61P 25/00 (2006.01) C07D 519/00 (2006.01)
Patent
CA 2564201
The invention relates to tetrahydronaphthyridine derivatives having formula (I) or (I~) and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. Said tetrahydronaphthyridine derivatives are H3 ligands and are useful in numerous diseases, disorders and conditions, in particular inflammatory, allergic and respiratory diseases, disorders and conditions.
L'invention concerne des dérivés de tétrahydronaphthyridine représentés par la formule (I) ou (I'), des procédés de préparation de ces dérivés, des intermédiaires utilisés dans la préparation de ces dérivés, des compositions qui renferment ces dérivés, ainsi que les différentes utilisations de ces dérivés. Les dérivés de tétrahydronaphthyridine sont des ligands de H3 qui s'utilisent pour soigner de multiples maladies, troubles et états pathologiques, en particulier les états, troubles et états pathologiques inflammatoires, allergiques et respiratoires.
Lunn Graham
Mathias John Paul
Strang Ross Sinclair
Pfizer Inc.
Torys Llp
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