Tetrahydronaphthyridines and aza derivatives thereof as...

Details Tetrahydronaphthyridines and aza derivatives thereof as... Tetrahydronaphthyridines and aza derivatives thereof as...

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/4375 (2006.01) A61P 1/00 (2006.01) A61P 9/00 (2006.01) A61P 25/00 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2719985

The invention relates to compounds of formula (I), wherein X1a, X1 to X5, R a, R b, n and R have the meaning as cited in the description and the claims. Said compounds are useful as Histamine H3 receptor antagonists. The invention also relates to pharmaceutical compositions, the preparation of such compounds as well as the production and use as medicament.

Cette invention concerne des composés de formule (I). Dans la formule (I), X1a, X1 à X5, Ra, Rb, n et R ont la signification indiquée dans la description et les revendications. Lesdits composés sont utiles à titre d'antagonistes des récepteurs d'histamine H3. L'invention concerne également des compositions pharmaceutiques, la préparation desdits composés ainsi que la leur production et utilisation à titre de médicament.

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