C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 405/04 (2006.01) A61K 31/40 (2006.01) A61K 31/41 (2006.01) A61K 31/435 (2006.01) A61K 31/54 (2006.01) A61P 25/00 (2006.01) A61P 29/00 (2006.01) C07D 205/00 (2006.01) C07D 307/00 (2006.01) C07D 405/06 (2006.01) C07D 407/12 (2006.01) C07D 417/04 (2006.01) C07D 491/10 (2006.01) C07D 498/04 (2006.01)
Patent
CA 2517422
The present invention relates to the compounds of the formula (I), wherein R1, R2, R3, R4, R5, R6, R7, R8, R9 and W are as defined herein, and pharmaceutically acceptable salts thereof; the compounds are of particular use in the treatment or prevention of depression, anxiety, pain, inflammation, migraine, emesis or postherpetic neuralgia.
La présente invention concerne des composés de formule (I), dans laquelle R?1¿, R?2¿, R?3¿, R?4¿, R?5¿, R?6¿, R?7¿, R?8¿, R?9¿ et W sont tels que définis dans cette invention, ainsi que des sels de ceux-ci, acceptables d'un point de vue pharmaceutique. Ces composés sont notamment utilisés pour traiter ou prévenir la dépression, l'angoisse, la douleur, les inflammations, la migraine, les vomissements ou les algies post-zostériennes.
Dirat Olivier
Elliott Jason Matthew
Huscroft Ian Thomas
Jelley Richard Alexander
Kulagowski Janusz Jozef
Merck Sharp & Dohme Limited
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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