C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 309/10 (2006.01) A61K 31/351 (2006.01) A61P 25/22 (2006.01) C07D 405/06 (2006.01) C07D 405/14 (2006.01)
Patent
CA 2493876
The present invention relates compounds of the formula (I), wherein R1, R2, R3, R4, R5, R6, R7, R8, R15 and R16 represent a variety of substituents; and pharmaceutically acceptable salts thereof. The compounds are of particular use in the treatment or prevention of depression, anxiety, pain, inflammation, migaine, emesis or postherpetic neuralgia.
L'invention concerne des composés de formule générale (I), dans laquelle R?1¿, R?2¿, R?3¿, R?4¿, R?5¿, R?6¿, R?7¿, R?8¿, R?15¿ et R?16¿ représentent une variété de substituants; et des sels pharmaceutiquement acceptables de ceux-ci. Lesdits composés s'avèrent particulièrement utiles dans le traitement ou la prévention de la dépression, l'anxiété, la douleur, l'inflammation, la migraine, les vomissements ou l'algie post-zostérienne.
Dirat Olivier
Elliott Jason Matthew
Kulagowski Janusz Jozef
Owen Simon Neil
Raubo Piotr Antoni
Merck Sharp & Dohme Limited
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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