C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 217/00 (2006.01) A61K 31/47 (2006.01) C07D 401/12 (2006.01) C07D 405/12 (2006.01) C07D 405/14 (2006.01) C07D 491/04 (2006.01) C07D 521/00 (2006.01)
Patent
CA 2483843
The present invention is directed to compounds of the formula I: I(wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, X, n and the dashed line are defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptor CCR-2.
L'invention concerne des composés représentés par la formule I (dans laquelle R?1¿, R?2¿, R?3¿, R?4¿, R?5¿, R?6¿, R?7¿, R?8¿, R?9¿, R?10¿, X, n et la ligne en traits interrompus sont tels que définis dans le descriptif), qui sont utiles comme modulateurs de l'activité des récepteurs des chimiokines, et en particulier comme modulateurs du récepteur des chimiokines CCR-2.
Butora Gabor
Goble Stephen D.
Guiadeen Deodialsingh
Jiao Richard
Kothandaraman Shankaran
Merck & Co. Inc.
Merck Sharp & Dohme Corp.
Merck Sharp & Dohme Limited
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
LandOfFree
Tetrahydropyranyl cyclopentyl tetrahydroisoquinoline... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Tetrahydropyranyl cyclopentyl tetrahydroisoquinoline..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Tetrahydropyranyl cyclopentyl tetrahydroisoquinoline... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1903082