Tetrahydropyrrolopyrimidinediones and their use as human...

C - Chemistry – Metallurgy – 07 – D

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C07D 487/04 (2006.01) A61K 31/519 (2006.01) A61P 11/00 (2006.01)

Patent

CA 2657956

Compounds of formula (I) and multimers thereof are inhibitors of human neutrophil elastase activity, and utility in the treatment of, e.g., COPD: wherein all the substituents are as defined in claim 1.

La présente invention concerne des composés de formule (I) et des multimères dérivés, en tant qu'inhibiteurs de l'activité de l'élastase neutrophile, et leur utilité dans le traitement de, p.ex., la BPCO (bronchopneumopathie chronique obstructive) sachant que tous les substituants sont tels que définis dans la revendication 1.

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