C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/04 (2006.01) A61K 31/517 (2006.01) A61K 31/519 (2006.01) A61P 29/00 (2006.01) A61P 37/00 (2006.01) C07D 239/91 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 409/12 (2006.01)
Patent
CA 2572084
Compounds are provided having the formula (I) wherein variables A1, A2, A3, A4, R1, R2, R3, R4, Q and L are described herein. The subject compounds are useful for treatment of inflammatory and immune conditions and diseases. Compositions and methods of treatment using the subject compounds are also provided. For example, the subject methods are useful for treatment of inflammatory and immune disorders and disease such as multiple sclerosis, rheumatoid arthritis, psoriasis, and inflammatory bowel disease.
La présente invention concerne des composés représentés par la formule (I) dans laquelle les variables A1, A2, A3, A4, R1, R2, R3, R4, Q et L sont telles que décrites dans les spécifications. Ces composés conviennent particulièrement au traitement d'états et affections de nature inflammatoires et immunitaires. L'invention concerne également des compositions et des procédés convenant à des traitements utilisant les composés de l'invention. Les pathologies concernées sont essentiellement la sclérose en plaque, la polyarthrite rhumatoïde, le psoriasis et l'inflammation intestinale.
Bergeron Philippe
Chen Xiaoqi
Deignan Jeffrey
Du Xiaohui
Duquette Jason A.
Amgen Inc.
Amgen Sf Llc
Osler Hoskin & Harcourt Llp
LandOfFree
Tetrahydroquinazolin-4(3h)-one-related and... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Tetrahydroquinazolin-4(3h)-one-related and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Tetrahydroquinazolin-4(3h)-one-related and... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1366663