C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 215/00 (2006.01) A61K 31/4709 (2006.01) A61P 25/00 (2006.01)
Patent
CA 2610873
The invention relates to ethynyl-substituted tetrahydroquinolinone derivatives as well as their pharmaceutically acceptable salts. The invention further relates to a process for the preparation of such compounds. The compounds of the invention are group I mGluR modulators and are therefore useful for the control and prevention of acute and/or chronic neurological disorders.
La présente invention a trait à des dérivés de tétrahydroquinolinone ainsi qu~à leurs sels pharmaceutiquement acceptables. L~invention concerne aussi un procédé de préparation de tels composés. Les composés de cette invention sont des modulateurs de groupe I mGluR et sont par conséquent utiles pour le contrôle et la prévention de désordres neurologiques aigus et/ou chroniques.
Danysz Wojciech
Henrich Markus
Jatzke Claudia
Jaunzeme Ieva
Jirgensons Aigars
Merz Pharma Gmbh & Co. Kgaa
Perley-Robertson Hill & Mcdougall Llp
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