C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 215/54 (2006.01) C07D 215/20 (2006.01) C07D 215/22 (2006.01) C07D 215/36 (2006.01) C07D 221/06 (2006.01) C07D 221/22 (2006.01) C07D 401/04 (2006.01) C07D 401/10 (2006.01) C07D 401/12 (2006.01) C07D 407/04 (2006.01) C07D 407/12 (2006.01) C07D 409/04 (2006.01) C07D 413/06 (2006.01) C07D 417/04 (2006.01) C07D 417/06 (2006.01)
Patent
CA 2556653
The invention relates to tetrahydroquinolinone derivatives as well as their pharmaceutically acceptable salts. The invention further relates to a process for the preparation of such compounds. The compounds of the invention are group I mGluR antagonists and are therefore useful for the control and prevention of acute and/or chronic neurological disorders. (see formula IA)
L'invention concerne des dérivés de tétrahydroquinolinone ainsi que leurs sels pharmaceutiquement acceptables. L'invention concerne également un procédé permettant de préparer ces composés. Les composés de l'invention sont des antagonistes mGluR du groupe I et sont, de ce fait, utilisés pour contrôler et prévenir les troubles neurologiques aigus et/ou chroniques.
Danysz Wojciech
Henrich Markus
Jaunzeme Ieva
Jirgensons Aigars
Kalvinsh Ivars
Merz Pharma Gmbh & Co. Kgaa
Perley-Robertson Hill & Mcdougall Llp
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