Tetrahymena heat inducible promoters and their use

C - Chemistry – Metallurgy – 12 – N

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C12N 15/85 (2006.01)

Patent

CA 2615075

The present invention relates to heat-inducible promoters of the heat shock protein family of the ciliate Tetrahymena thermophila, especially a promoter having the nucleotide sequence of Seq. ID No. 1 or promoter-effective fragments thereof. Furthermore the use of heat-inducible promoters of the present invention for the expression of homologous and/or heterologous proteins in the ciliate Tetrahymena thermophila is claimed.

L'invention concerne des promoteurs thermoinductibles de la famille des protéines de choc thermique de la Tetrahymena thermophila ciliée, et plus particulièrement un promoteur possédant la séquence nucléotidique de Seq. ID No. 1 ou de ses fragments efficaces de promoteur. L'invention revendique également l'utilisation de promoteurs thermoinductibles pour l'expression de protéines homologues et/ou hétérologues dans la Tetrahymena thermophila ciliée.

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