Tetrapropylammonium tetrathiomolybdate and related compounds...

A - Human Necessities – 61 – K

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A61K 31/14 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2493341

Disclosed are copper-binding compounds with improved properties and methods of using such compounds in the prevention and treatment of angiogenic diseases, such as cancer. Advantages of the invention include the enhanced stability of the compounds, which is achieved without reduction in efficacy. Pharmaceutical compositions, therapeutic kits and combination treatment methods and uses are also provided.

L'invention concerne des composés à liaison du cuivre présentant des propriétés améliorées, et des procédés consistant à utiliser ces composés pour prévenir et traiter des maladies angiogéniques, telles que le cancer. Les composés décrits dans cette invention présente une meilleure stabilité sans réduction de l'efficacité. La présente invention concerne également des compositions pharmaceutiques, des trousses thérapeutiques, des polythérapies, ainsi que des utilisations.

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