Tetrazole compounds as orexin receptor antagonists

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 403/12 (2006.01) A61K 31/4155 (2006.01) A61K 31/4439 (2006.01) A61P 25/00 (2006.01) C07D 401/14 (2006.01) C07D 405/14 (2006.01) C07D 409/14 (2006.01)

Patent

CA 2726102

The invention relates to tetrazole compounds of formula (I) wherein X, Y, Z, R1, R2 and R3 are as described in the description; to pharmaceutically acceptable salts thereof, and to the use of such compounds use as medicaments, especially as orexin receptor antagonists.

La présente invention concerne des composés tétrazoliques de formule (I) dans laquelle X, Y, Z, R1, R2 et R3 sont tels que décrits dans la description ; leurs sels pharmaceutiquement acceptables, et lutilisation de tels composés comme médicaments, particulièrement comme antagonistes des récepteurs à lorexine.

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