C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 498/18 (2006.01) A61K 31/395 (2006.01)
Patent
CA 2303934
A compound having formula (I) or a pharmaceutically acceptable salt or prodrug thereof, is an immunomodulary agent and is useful in the treatment of restenosis and immune and autoimmune diseases. Also, disclosed are cancer-, fungal growth-, restenosis-, post-transplant tissue rejection- and immune- and autoimmune disease-inhibiting compositions and a method of inhibiting cancer, fungal growth, restenosis, post-transplant tissue rejection, and immune and autoimmune disease in a mammal, with minimized side-effects due to shortened half-lives. (see formula I)
Un composé ayant la formule (I) ou un sel ou bien un promédicament pharmaceutiquement acceptable de celui-ci constitue un agent immunomodulateur et est utile dans le traitement de la resténose et de maladies immunes et auto-immunes. Sont également décrites des compositions inhibant le cancer, la prolifération fongique, la resténose, le rejet de tissus après greffe, des maladies immunes et auto-immunes ainsi qu'une méthode d'inhibition du cancer, de la prolifération fongique, de la resténose, du rejet de tissu après greffe et de maladies immunes et auto-immunes chez un mammifère.
Abbott Laboratories
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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