Tetrazole derivatives

C - Chemistry – Metallurgy – 07 – D

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C07D 257/04 (2006.01) A01N 43/713 (2006.01)

Patent

CA 1208227

ABSTRACT OF THE DISCLOSURE: Triidoallyl- or iodopropargyl-substituted tetrazole compounds are provided which are prepared by reacting substituted tetrazole compound with reactive derivatives of corresponding triidoallyl alcohol or iodopropargyl alcohol or by iodinating propargyltetrazole compounds, as well as antibacterial and antifungal compositions for medicinal, agricultural and industrial fields which contain as active ingredient said tetrazole compounds. The tetrazole compounds have the following general structure Image wherein X represents a group of -C?CI or a group of Image when X is a group of -C?CI, R represents an alkyl group, a benzyl group, a phenyl group or a phenyl group substituted by one or more groups selected from the class consisting of alkoxy, halo, trifluoromethyl, cyano, hydroxy, alkyl, carbamoyl, nitro, mono-alkylamino, di-alkylamino and carboxy, provided that R cannot be a 3-chloro-2-nitrophenyl group; and when X is a group of Image , R represents an alkyl group having two or more carbon atoms, a benzyl group or a phenyl group substituted by one or more groups selected from the class consisting of alkoxy, halo, trifluoromethyl, cyano, hydroxy, alkyl, carbamoyl, nitro, mono-alkylamino, di-alkyl- amino and carboxy, provided that R cannot be a 3-chloro-2-nitrophenyl group.

439914

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