Tetrazole derivatives and processes for their preparation

Details Tetrazole derivatives and processes for their preparation Tetrazole derivatives and processes for their preparation

C - Chemistry, Metallurgy

07

D

260/312

C07D 257/04 (2006.01) C07C 205/37 (2006.01) C07C 205/60 (2006.01)

Patent

CA 1118427

ABSTRACT OF THE DISCLOSURE New tetrazole derivatives of the general formula: Image I [wherein R1 represents a halogen atom, a straight- or branched- chain alkyl, alkoxy, alkylthio, alkylsulphinyl, alkylsulphonyl or alkylsulphamoyl group, each such group containing from 1 to 6 carbon atoms, a dialkylsulphamoyl, dialkylamino, or dialkylcarbamoyl group (wherein the two alkyl groups may be the same or different and each contains from 1 to 4 carbon atoms), a straight- or branched-chain alkanoyl, alkoxycarbonyl, alkoxycarbonylamino, alkylcarbamoyl or alkanoylamino group containing from 2 to 6 carbon atoms, a cycloalkylcarbonyl group containing from 3 to 8 carbon atoms in the cycloalkyl moiety, or a hydroxy, formyl, nitro, trifluoromethyl, trifluo- roacetyl, aryl, benzyloxycarbonylamino, amino, sulphamoyl, cyano, carboxy, carbamoyl, benzyloxy, aralkanoyl or benzoyl group, and m represents zero or an integer 1, 2 or 3, the substituents R1 being the same or different when m represents 2 or 3] possess pharmacological properties, in particular properties of value in the treatment of allergic conditions.

314318

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