Tetrazolylphenylboronic acid intermediates for the synthesis...

Details Tetrazolylphenylboronic acid intermediates for the synthesis... Tetrazolylphenylboronic acid intermediates for the synthesis...

C - Chemistry, Metallurgy

07

F

C07F 5/02 (2006.01) C07F 5/05 (2006.01) C07F 7/10 (2006.01)

Patent

CA 2123900

Novel tetrazolylphenylboronic acids, methods for their preparation and methods for preparing biphenyltetrazole compounds which are antiotensin II receptor antagonists or which are useful intermediates to prepare angiotensin II receptor antagonists. An illustrative biphenyl tetrazole compound is 2-n-butyl-4-chloro-1-[(2'-(tetrazol-5-yl)-1,1'-biphenyl-4-yl)methyl]-1H-im- idazole-5-methanol, potassium salt.

Nouveaux acides tétrazolylphénylboriques; méthode d'obtention et procédé pour préparer des biphényltétrazoles, qui sont des antagonistes des récepteurs de l'angiotensine II ou des intermédiaires utiles pour préparer ces antagonistes. Exemple de biphényltétrazole : le sel de potassium de 2-n-butyl-4-chloro-1-¢(2'-(tétrazol-5-yl)-1,1'-biphényl-4-yl)méthyl!- 1H-imidazole-5-méthanol.

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