C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 487/22 (2006.01) A61K 31/40 (2006.01) A61K 31/555 (2006.01) A61K 47/48 (2006.01) A61P 9/00 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2334809
Texaphyrin/chemotherapeutic drug conjugates, optionally including a platinum (II) or platinum (IV) metal chelating site and/or complex, are useful for treating atheroma, tumors and other neoplastic tissue, neovascular-related diseases, as well as other conditions that are typically responsive to chemotherapy, radiation sensitization and photodynamic therapy.
La présente invention concerne des conjugués de texaphyrine et d'agents chimiothérapeutiques, qui comprennent éventuellement un site chélatant et/ou de complexation de platine (II) ou de platine (IV), utiles pour le traitement d'athéromes, de tumeurs et d'autres tissus néoplastiques, de maladies de cause néovasculaire, aussi bien que pour d'autre états qui répondent typiquement à une chimiothérapie, à une sensibilisation de radiation et à une thérapie photodynamique.
Anzenbacher Pavel Jr.
Carvalho Joan
Magda Darren
Mody Tarak
Sessler Jonathan L.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Board Of Regents The University Of Texas System
Pharmacyclics Inc.
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