Tgf beta 1 specific antibodies

C - Chemistry – Metallurgy – 07 – K

Patent

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C07K 16/22 (2006.01) G01N 33/577 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2607448

Antibodies specific for mature TGF Beta 1 over mature TGF Beta 2 and mature TGF Beta 3 are provided. The antibodies are characterized by CDR3 of the heavy- chain GYRX1X2X3Y wherein Xl is W or A, X2 is F or L, X3 is A, E or Y.

L'invention concerne des compositions de liaison isolées et/ou de recombinaison, et des réactifs s'y rapportant. L'invention concerne également des procédés permettant d'utiliser ces réactifs ainsi que des trousses de diagnostic.

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