Tgf-beta compositions

A - Human Necessities – 61 – K

Patent

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A61K 38/18 (2006.01)

Patent

CA 2042973

RAN 4105/133 Abstract Transforming growth factor-beta (TGF-beta) is enhanced in its therapeutic activity against neoplastic diseases, especially carcinomas and melanomas, by utilizing it in combination with a synergistic effective amount of a polyunsaturated fatty acid (PUFA) or a derivative thereof. In a preferred embodiment, type 1 transforming growth factor beta (TGF-.beta.1) exhibits enhanced anti-neoplastic activity when utilized in combination with an .omega.-3 or .omega.-6 polyunsaturated fatty acid such as linoleic, alpha-linolenic, arachidonic, gamma-linolenic, dihomogammalinolenic, eicosapentaenoic and docosahexaenoic acid.

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