Tgf-beta induced gene and protein

Details Tgf-beta induced gene and protein Tgf-beta induced gene and protein

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) C07K 14/435 (2006.01) C07K 14/71 (2006.01)

Patent

CA 2088804

ABSTRACT OF THE DISCLOSURE A new TGF-.beta. induced gene and protein is described. Treatment of TGF-.beta. growth arrested cells induces the production of a novel gene which encodes a 683 amino acid protein, designated BIG-H3, that contains four homologous repeat regions and which may represent a cell surface recognition molecule. This gene and protein is induced in mammalian cells, and specifically human cells, upon treatment with TGF-.beta..

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