Th2 differentiation inhibitors

Details Th2 differentiation inhibitors Th2 differentiation inhibitors

A - Human Necessities

61

K

A61K 31/09 (2006.01) A61K 31/05 (2006.01) A61K 31/075 (2006.01) A61K 31/095 (2006.01) A61K 31/135 (2006.01) A61K 31/136 (2006.01) A61K 31/15 (2006.01) A61K 31/235 (2006.01) A61K 31/44 (2006.01) A61K 31/4418 (2006.01) A61K 31/495 (2006.01) A61K 31/4965 (2006.01) A61K 31/50 (2006.01) A61K 31/505 (2006.01) A61P 1/04 (2006.01) A61P 15/00 (2006.01) A61P 21/04 (2006.01) A61P 37/06 (2006.01) C07C 211/50 (2006.01) C07C 217/80 (2006.01) C07C 251/58 (2006.01) C07D 213/64 (2006.01) C07D 213/74 (2006.01) C07D 213/77 (2

Patent

CA 2375982

Th2 differentiation inhibitors which contain compounds represented by general formula (I), prodrugs thereof, pharmaceutically acceptable salts thereof or solvates of the same, wherein the rings A, B and C are each an aromatic carbon ring, a heterocycle, etc.; X represents a single bond, -O-, -CH2-, -NH-, -SO-, etc.; Y represents hydrogen, optionally substituted lower alkyl, optionally substituted lower alkenyl, etc.; and V1 and V2 represent each a single bond, - O-,-NH-, -OCH2-, etc.

L'invention concerne des inhibiteurs de différenciation Th2 contenant des composés représentés dans la formule générale (I), des promédicaments, des sels pharmaceutiquement acceptables et des solvates de ces composés. Dans la formule, les noyaux A, B et C représentent chacun un noyau aromatique de carbone, un hétérocycle, etc.; X représente une liaison simple, -O-,-CH¿2?-,-NH-,-SO-, etc.; Y représente l'hydrogène, un alkyle inférieur éventuellement substitué, un alcényle inférieur éventuellement subsituté, etc.; et V?1¿ et V?2¿ représentent chacun un noyau simple,-O-,-NH-,-OCH¿2?-, etc.

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