C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/04 (2006.01) A61K 31/4035 (2006.01) A61K 31/4439 (2006.01) A61K 31/454 (2006.01) A61K 31/536 (2006.01) A61P 35/00 (2006.01) A61P 35/04 (2006.01) C07D 209/44 (2006.01) C07D 209/46 (2006.01) C07D 211/84 (2006.01) C07D 211/88 (2006.01) C07D 413/04 (2006.01) C07D 471/04 (2006.01)
Patent
CA 2538864
Thalidomide analogs that modulate tumor necrosis factor alpha (TNF-.alpha.) activity and angiogenesis are disclosed. In particularly disclosed embodiments, the thalidomide analogs are isosteric sulfur-containing analogs. Also disclosed are methods of treating a subject with the analogs.
L'invention concerne des analogues du thalidomide modulant l'activité et l'angiogénèse du facteur alpha de nécrose des tumeurs (TNF-?). Dans des modes de réalisation spécifiques, les analogues du thalidomide sont des analogues isostères renfermant du soufre. L'invention concerne également des méthodes de traitement d'un sujet au moyen des analogues.
Brossi Arnold
Figg William D.
Giordano Tony
Greig Nigel H.
Holloway Harold
Brossi Arnold
Giordano Tony
Smart & Biggar
The Government Of The United States Of America As Represented By The Se Cretary Of The Department Of Health And
LandOfFree
Thalidomide analogs as tnf-alpha modulators does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Thalidomide analogs as tnf-alpha modulators, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Thalidomide analogs as tnf-alpha modulators will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-2029267