The alginate having low molecular weight, methods of...

C - Chemistry – Metallurgy – 08 – B

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C08B 37/04 (2006.01) A61K 31/734 (2006.01)

Patent

CA 2430277

The alginic acid or the salts thereof having average molecular weight of between about 5,000 -20,000 daltons and exhibiting intrinsic viscosity of between 1 - 20 measured by the Ubbelohde viscometer are provided. Most of the alginates have molecular weight of between 1,000 - 30,000 daltons. They are prepared form a high molecular weight alginic acid by means of decomposition, ultrafiltration and nanofiltration membran. they are of uses for prevention and treatment of hypertension, primary hyperaldosteronism and for reducing blood sugar.

L'invention concerne un acide alginique ou ses sels présentant un poids moléculaire moyen compris entre 5.000 et 20.000 daltons et faisant preuve d'une viscosité intrinsèque d'environ 1 à 20 selon le viscosimètre d'Ubbelohde. La plupart des alginates présentent un poids moléculaire compris entre 1.000 et 30.000 daltons. Ces alginates sont obtenus à partir d'un acide alginique à poids moléculaire élevé par le biais de la décomposition et de l'ultrafiltration et de la nanofiltration. L'invention trouve une application dans la prévention et le traitement de l'hypertension, de hyperaldostéronisme primaire et dans la réduction du taux de sucre dans le sang.

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