The bioresolution of n-acylazetidine-2-carboxylic acids

C - Chemistry – Metallurgy – 12 – P

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C12P 41/00 (2006.01) C07D 205/04 (2006.01) C12P 17/10 (2006.01) C12Q 1/44 (2006.01)

Patent

CA 2259402

There is provided a process for obtaining an enantiomerically enriched N- acylazetidine-2-carboxylic acid, which process compri ses the biotransformation of a racemic N-acylazetidine-2-carb oxylic acid ester with an enzyme that displays enantiospecificity.

Procédé d'obtention d'acides N-acylazétidine-2-carboxyliques à enrichissement énantiomorphe, consistant en la bio-transformation d'un ester racémique d'acides N-acylazétidine-2-carboxyliques avec un enzyme présentant une émantiospécificité.

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