The butyrophilin gene promoter and uses thereof

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/85 (2006.01) A01K 67/027 (2006.01) A61K 49/00 (2006.01) C07K 14/705 (2006.01) C12N 15/12 (2006.01) C12P 21/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2260020

The DNA sequence of the mouse butyrophilin gene and its promoter is disclosed and analyzed. In addition, expression of the mouse butyrophilin gene is characterized. Further, use of the butyrophilin promoter for expressing polypeptides in the milk of a transgenic animal and for screening substances for carcinogenicity is disclosed.

La séquence d'ADN du gène de butyrophiline murin et de son promoteur est présentée et analysée. En outre, l'expression de ce gène de butyrophiline murin est caractérisée. L'utilisation du promoteur de butyrophiline pour exprimer des polypeptides dans le lait d'un animal transgénique et pour cribler des substances en fonction de leur cancérogénicité est également présentée.

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