The combination of a serotonin reuptake inhibitor and a...

A - Human Necessities – 61 – K

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A61K 31/517 (2006.01) A61K 31/00 (2006.01) A61K 31/135 (2006.01) A61K 31/137 (2006.01) A61K 31/15 (2006.01) A61K 31/343 (2006.01) A61K 31/405 (2006.01) A61K 31/445 (2006.01) A61K 31/451 (2006.01) A61K 31/4525 (2006.01) A61K 31/496 (2006.01) A61K 31/519 (2006.01) A61K 31/55 (2006.01) A61K 31/551 (2006.01) A61K 33/36 (2006.01) A61K 45/06 (2006.01) C12Q 1/00 (2006.01) G01N 33/00 (2006.01) G01N 33/50 (2006.01) G01N 33/94 (2006.01)

Patent

CA 2393470

The present invention relates to the use of compounds and compositions of compounds having serotonin reuptake inhibiting activity and 5-HT2C antagonistic, partial agonistic or inverse agonistic activity for the for the treatment of depression and other affective disorders. The combined serotonin reuptake inhibiting effect and the 5-HT2C antagonistic, partial agonistic or inverse agonistic effect may reside within the same chemical compound or in two different chemical compounds.

La présente invention concerne l'utilisation de composés et de compositions présentant une activité inhibitrice du recaptage de la sérotonine et une activité antagoniste, agoniste partielle ou agoniste inverse de 5-HT¿2C?. Ces composés et ces compositions sont destinés au traitement de la dépression et d'autres troubles affectifs. L'effet inhibiteur du recaptage de la sérotonine et l'effet antagoniste, agoniste partiel ou agoniste inverse de 5-HT¿2C? peuvent provenir du même composé ou de deux composés chimiques différents.

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