The combination of anticholinergics and glucocorticoids for...

A - Human Necessities – 61 – K

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A61K 31/4015 (2006.01) A61K 31/56 (2006.01) A61K 31/573 (2006.01) A61P 11/00 (2006.01) A61P 11/06 (2006.01)

Patent

CA 2551780

The present invention describes the combination of topically inhaled medicinal formulations comprising an anticholinergic component preferably glycopymolate and a glucocorticosteroid component and its use in the symptomatic and prophylactic treatment of diseases of the respiratory tract, especially with an obstructive component or underlying inflammation like asthma and chronic obstructive pulmonary disease (COPD). It further comprises the presentation of this combination in a locally applied (inhaled) formulation and application in an inhalation device for instance in the Novolizer.

La présente invention se rapporte à la combinaison de formulations médicinales inhalées de manière topique, comportant un composant anticholinergique, de préférence du glycopyrrolate, et un composant glucocorticostéroïde, ainsi qu'à l'utilisation de cette combinaison pour le traitement symptomatique et prophylactique des maladies respiratoires, en particulier associées à une composante obstructive ou à une inflammation sous-jacente, telles que l'asthme et la broncho-pneumopathie chronique obstructive (COPD). L'invention se rapporte également à la présentation de cette combinaison dans une formulation appliquée localement (inhalée) ainsi qu'à l'application dans un dispositif d'inhalation, par exemple dans le Novolizer.

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