A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 33/24 (2006.01) A61K 31/16 (2006.01) A61K 31/195 (2006.01) A61K 31/40 (2006.01) A61K 31/405 (2006.01)
Patent
CA 2515424
Synergistic compositions and methods are disclosed for using cruciferous indoles with iron/zinc chelators in the treatment of papillomavirus-related conditions. These synergistic compositions of diindolylymethane (DIM), related trimeric derivatives, and related indole derivatives include combinations with deferoxamine, deferiprone, bipyridyl, Desferri-exochelin, picolinic acid, 3- hydroxypicolinic acid, and sodium butyrate as iron/zinc chelators. The methods described comprise more effective therapies for common cutaneous warts (verrucae) and related dysplasias of the oropharynx, genitalia, and uterine cervix.
L'invention concerne des compositions synergiques et des procédés correspondants visant à l'utilisation d'indoles avec des chélateurs.fer/zinc, dans le traitement d'états liés au papillomavirus. Ces compositions synergiques de di-indolylyméthane (DIM), de dérivés trimères apparentés, et de dérivés de l'indole apparentés comprennent des combinaisons renfermant les composés ci-après : deferoxamine, deferiprone, bipyridyle, Desferri-exocheline, acide picolinique, acide 3-hydroxypicolinique et butyrate de sodium, comme chélateurs fer/zinc. Les procédés selon l'invention comprennent des thérapies plus efficaces pour des affections de l'épiderme courantes (verrues) et des dysplasies apparentées de l'oro-pharynx, des organes génitaux et du col de l'utérus.
Bioresponse Llc
Osler Hoskin & Harcourt Llp
LandOfFree
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