C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 239/88 (2006.01) A61K 31/517 (2006.01) A61K 31/519 (2006.01) A61P 3/00 (2006.01) A61P 3/04 (2006.01) A61P 3/06 (2006.01) A61P 3/10 (2006.01) A61P 9/00 (2006.01) A61P 9/10 (2006.01) C07D 239/86 (2006.01) C07D 239/90 (2006.01) C07D 239/91 (2006.01) C07D 471/04 (2006.01) C07D 487/04 (2006.01)
Patent
CA 2750859
The compounds according to formula VIII, their pharmaceutically acceptable acid or base addition salts, and the uses thereof is disclosed. These compounds and their pharmaceutically acceptable acid or base addition salts can be used for the preparing a medicament for modulating estrogen related receptor (ERR), and treating metabolic diseases, such as high blood fat, fatty liver, hyperglycemia, diabetes, obesity, etc. The definition of the groups of the formula is defined as the description. (see formula VIII)
La présente invention concerne les composés représentés par la formule (I), leurs sels d'addition acides ou basiques pharmaceutiquement admis, et leurs utilisations. Ces composés et leurs sels d'addition acides ou basiques pharmaceutiquement admis conviennent à l'élaboration d'un médicament servant à moduler les récepteurs liés aux strogènes ou ERR (Estrogen Related Receptors) et à traiter des maladies métaboliques telles que l'hyperlipémie, la stéatose hépatique, l'hyperglycémie, le diabète, l'obésité. Les groupes de la formule sont tels que décrits dans la description.
Ding Ke
Kang Zhanfang
Wong Chiwai
Zhou Xi
Guangzhou Institute Of Biomedicine And Health Chinese Academy Of Scienc Es
Ridout & Maybee Llp
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