C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 5/10 (2006.01) A61K 48/00 (2006.01) A61P 19/08 (2006.01) A61P 25/28 (2006.01) A61P 37/00 (2006.01) A61K 35/12 (2006.01) A61K 38/00 (2006.01) C12N 5/06 (2006.01)
Patent
CA 2349497
The invention relates to a method for producing cells which are suitable for treating the human body. According to said method, (a) cells are taken from the human body; (b) the cells obtained in step (a) are transfected in vitro with at least one gene coding for a growth and/or differentiation factor, which gene is under the control of a promoter; so that the cells from step (b) are capable of differentiation in a desired manner once they are re-introduced into the human body. The invention also relates to cells which are obtained by said method and to their use for producing a medicament for treating diseases.
L'invention concerne un procédé permettant de préparer des cellules adaptées pour traiter le corps humain, selon lequel (a) des cellules sont prélevées sur le corps humain; (b) les cellules obtenues à l'étape (a) sont transfectées in vitro avec au moins un gène pour un facteur de croissance et/ou de différenciation, qui se trouve sous le contrôle d'un promoteur, de sorte que les cellules de l'étape (b) soient en mesure après avoir été replacées dans le corps humain d'effectuer des différenciations de manière voulue. L'invention concerne également des cellules pouvant être obtenues à l'aide dudit procédé et leur utilisation pour préparer un médicament pour traiter des affections.
Havemann Klaus
Muller Rolf
Sedlacek Hans-Harald
Aventis Pharma Deutschland Gmbh
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
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