The genome of the hiv-1 inter-subtype (c/b') and use thereof

C - Chemistry – Metallurgy – 12 – N

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C12N 15/49 (2006.01) A61K 39/21 (2006.01) A61P 31/18 (2006.01) C07K 14/16 (2006.01) C07K 16/10 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2391560

The invention relates to a polynucleotide, comprising a nucleic acid sequence according to SEQ ID NO:1, 2 or 3, fragments or derivatives thereof, or a polynucleotide hybridised with the nucleic acid sequence according to SEQ ID NO:1, 2 or 3. The invention further relates to polypeptides coded from said nucleotide sequence, or fragment, or derivative of the nucleic acid sequence according to SEQ ID NO:1, 2 or 3. The polynucleotides and polypeptides may be used as medicaments, vaccines or diagnostics, in particular for the treatment, prophylaxis and diagnosis of HIV infections.

La présente invention concerne un polynucléotide comprenant une séquence d'acide nucléique selon SEQ ID NO:1, 2 ou 3, ou un fragment ou dérivé de celle-ci, ou un polynucléotide qui est hybridé avec la séquence d'acide nucléique selon SEQ ID NO: 1, 2 ou 3. Cette invention concerne également des polypeptides codés par la séquence nucléotidique ou le fragment ou dérivé de la séquence nucléotidique selon SEQ ID NO: 1, 2 ou 3. Les polynucléotides et polypeptides peuvent être utilisés comme produits pharmaceutiques, vaccins ou agents de diagnostic, en particulier pour le traitement, la prévention et le diagnostic d'infections par le VIH.

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