C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/57 (2006.01) A61K 38/04 (2006.01) A61K 38/16 (2006.01) A61P 7/00 (2006.01) C07K 7/08 (2006.01) C07K 14/705 (2006.01) C07K 14/72 (2006.01) C07K 16/18 (2006.01) C07K 16/28 (2006.01) C12N 5/10 (2006.01) C12N 15/12 (2006.01) C12P 21/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01) G01N 33/554 (2006.01) G01N 33/566 (2006.01)
Patent
CA 2439607
This invention relates to nucleic acid encoding guinea pig PAR 4 and to the protein encoded thereby. The guinea pig DNA and protein are useful for the development of models of human platelet aggregation. The invention further relates to an animal model to assess the role of PAR antagonists in thrombosis.
L'invention concerne un acide nucléique codant le récepteur 4 activé par la protéinase (PAR) du cobaye et à la protéine codée par cet acide. L'ADN du cobaye et la protéine servent au développement de modèles d'agrégation de plaquettes humaines. Cette invention porte aussi sur un modèle animal pouvant jouer le rôle d'antagonistes de PAR dans les thromboses.
Addo Michael F.
Andrade-Gordon Patricia
Darrow Andrew L.
Derian Claudia K.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
Ortho-Mcneil Pharmaceutical Inc.
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