The improved long acting gi and esophageal protectant

Details The improved long acting gi and esophageal protectant The improved long acting gi and esophageal protectant

A - Human Necessities

61

K

A61K 9/107 (2006.01) A61K 9/00 (2006.01) A61K 9/68 (2006.01)

Patent

CA 2192961

A bioadherent, orally ingestible system, which comprises: a water-in-oil emulsion system having at least two phases, one phase comprises from about 75 % to about 99 % by volume of an internal hydrophylic phase and the other phase comprises from about 25 % to about 1 % by volume of an external hydrophobic phase, wherein the external hydrophobic phase comprises two components, one component being about 3 % to about 97 % by volume of the hydrophobic phase of a hydrophobic oil and the other being about 97 % to about 3 % of an emulsifier having a HLB value less than about 10.

Agent bioadhésif et ingérable par voie orale composé d'une émulsion eau-dans-huile possédant au moins deux phases: une phase composée de 75 % à 99 % en volume environ d'une phase hydrophile interne et une autre phase composée de 25 % à 1 % en volume environ d'une phase hydrophobe externe, cette dernière comprenant deux constituants: un constituant représentant de 3 % à 97 % en volume environ de la phase hydrophobe d'une huile hydrophobe et un autre constituant représentant de 97 % à 3 % environ d'un émulsifiant possédant une valeur de rapport hydrophile-lipophile inférieure à 10 environ.

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