The ltr region of msrv-1 and the proteins it encodes, and...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/48 (2006.01) C07K 14/15 (2006.01) C07K 16/10 (2006.01) C12N 15/11 (2006.01) C12Q 1/68 (2006.01) G01N 33/569 (2006.01)

Patent

CA 2362524

The invention relates to a nucleotide fragment of a LTR-RU5 region comprising a nucleotide sequence which encodes the expression of a protein, wherein said protein comprises a peptide sequence selected from SEQ ID NO: 2, SEQ ID NO: 3 and SEQ ID NO: 4, and a complementary nucleotide fragment; a probe and a primer hybridizing with said fragment; a protein encoded by said fragment and a polypeptide; an antibody directed against said protein or said polypeptide; and a process for detecting the presence of MSRV-1 retrovirus using a probe or an antibody of the invention.

L'invention concerne un fragment nucléotidique de région LTR-RU5, comprenant une séquence nucléotidique codant l'expression d'une protéine. Ladite protéine comprend une séquence peptidique pouvant être SEQ ID NO: 2, SEQ ID NO: 3 et SEQ ID NO: 4, et un fragment nucléotidique complémentaire. L'invention concerne en outre une sonde et une amorce capables d'hybridation avec ce fragment; une protéine codée par ledit fragment et un polypeptide; un anticorps dirigé contre la protéine ou le polypeptide en question; et un procédé de détection du rétrovirus MSRV-1 au moyen d'une sonde ou d'un anticorps décrits dans l'invention.

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