The medical treatment using thyroid hormones

A - Human Necessities – 61 – K

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A61K 31/195 (2006.01)

Patent

CA 2165822

Central nervous system ischemia is prevented or minimised in a patient who has suffered an acute insult by administering a protective amount of a thyroid hormone such as levothyroxine, liothyronine, L-3,3',5'-triiodothyronine or L,3,5-diiodothyronine, preferably in the form of their sodium salts. An initial bolus dose of the thyroid hormone may be given before initiation of the continuous administration. The treatment is particularly applicable to the treatment of cerebral ischemia following cardiac arrest.

On empêche ou on minimise l'ischémie du système nerveux central chez un patient qui a souffert d'une lésion aiguë, par l'administration d'une dose protectrice d'une hormone thyroïdienne telle que la lévothyroxine, la liothyronine, la L-3,3',5'-triiodothyronine ou la L-3,5-diiodothyronine, de préférence sous la forme de leurs sels de sodium. Une dose initiale ponctuelle de l'hormone thyroïdienne peut être donnée avant l'administration continue. Le traitement est particulièrement utile contre les ischémies cérébrales consécutives à un arrêt cardiaque.

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