The n-alkylation of amines

C - Chemistry – Metallurgy – 07 – C

Patent

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C07C 211/03 (2006.01) B01J 23/72 (2006.01) C07C 209/16 (2006.01) C07C 209/60 (2006.01) C07D 295/023 (2006.01) C07D 295/03 (2006.01)

Patent

CA 2228613

In a process for the N-alkylation of amines in which alcohols are reacted with alkylamines or dialkylamines in the presence of hydrogen, the reaction takes place on a catalyst based on copper and magnesium silicate and containing, in each case independently, 0 to 2 % by weight of BaO, Cr2O3 and/or ZnO. The amines employed are mono- or dimethylamine or mono- or diethylamine, the alcohols employed are .alpha.,.omega.-diols, in particular diethylene glycol or pentanediol. In particular there is reaction of diethylene glycol with monomethylamine and/or monoethylamine to give N-methylmorpholine and/or N-ethylmorpholine.

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