The preparation of salts of pharmaceutical active substances...

Details The preparation of salts of pharmaceutical active substances... The preparation of salts of pharmaceutical active substances...

C - Chemistry, Metallurgy

07

C

C07C 51/41 (2006.01) A61K 9/16 (2006.01) A61K 31/185 (2006.01) A61K 31/192 (2006.01) A61K 31/40 (2006.01) A61K 31/405 (2006.01) A61K 31/41 (2006.01) A61K 31/60 (2006.01)

Patent

CA 2208495

A process for preparing salts of pharmaceutical active substances which have acidic groups by reacting the carboxylic acids with a base in the melt, wherein the acids are reacted with at least the stoichiometric amount of a base in an extruder.

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