The recombinant production of proteins in yeast

Details The recombinant production of proteins in yeast The recombinant production of proteins in yeast

C - Chemistry, Metallurgy

12

N

C12N 15/81 (2006.01) C07K 14/815 (2006.01) C12P 21/00 (2006.01)

Patent

CA 2175068

A process for the recombinant production of proteins in yeast in which the yeast is transformed with an expression cassette containing the coded structural components: L-A-P-GEN, in which L is a leader sequence of an animal peptidic neurohormone, A is an adaptor generating an alpha helix structure, P is a processing signal and GEN is a structure gene for the desired protein.

Procédé pour la production de protéines par recombinaison dans une levure, caractérisé en ce que la levure est transformée avec une cassette d'expression qui contient les éléments structuraux suivant sous forme codée: L -A - P - GEN, formule dans laquelle L désigne une séquence-guide d'une neurohormone peptidique animale, A un adaptateur produisant une structure en hélice alpha, P un signal de traitement et GEN un gène de structure pour la protéine souhaitée.

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