The severe acute respiratory syndrome coronavirus

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/50 (2006.01) A61K 31/00 (2006.01) A61K 31/70 (2006.01) A61K 35/76 (2006.01) A61K 38/16 (2006.01) A61K 39/215 (2006.01) C07H 21/00 (2006.01) C07K 14/165 (2006.01) C07K 16/10 (2006.01) C12N 5/10 (2006.01) C12N 7/01 (2006.01) C12N 7/04 (2006.01) C12N 15/86 (2006.01) C12Q 1/25 (2006.01) C12Q 1/37 (2006.01) C12Q 1/68 (2006.01) C12Q 1/70 (2006.01) G01N 33/569 (2006.01)

Patent

CA 2522379

An outbreak of a virulent respiratory virus, now known as Severe Acute Respiratory Syndrome (SARS), was identified in Hong Kong, China and a growing number of countries around the world in 2003. The invention relates to nucleic acids and proteins from the SARS coronavirus. These nucleic acids and proteins can be used in the preparation and manufacture of vaccine formulations, diagnostic reagents, kits, etc. The invention also provides methods for treating SARS by administering small molecule antiviral compounds, as well as methods of identifying potent small molecules for the treatment of SARS.

On a identifié une épidémie provoquée par un virus respiratoire, connu maintenant comme syndrome respiratoire aigu grave, à Hong Kong, en Chine et dans un nombre croissant de pays à travers le monde en 2003. L'invention a trait à des acides nucléiques et des protéines à partir du coronavirus du syndrome respiratoire aigu grave. Ces acides nucléiques et ces protéines peuvent être utilisés dans la préparation et la fabrication de formulations vaccinales, de réactifs de diagnostic, de trousses, et analogues. L'invention a également trait à des procédés pour le traitement du syndrome respiratoire aigu grave par l'administration de composés antiviraux de petites molécules, ainsi qu'à des procédés d'identification de petites molécules efficaces pour le traitement du syndrome respiratoire aigu grave.

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