The tuberculosis rv2386c protein, compositions and uses thereof

Details The tuberculosis rv2386c protein, compositions and uses thereof The tuberculosis rv2386c protein, compositions and uses thereof

C - Chemistry, Metallurgy

12

N

C12N 15/60 (2006.01) A61K 38/51 (2006.01) A61K 38/52 (2006.01) A61K 39/04 (2006.01) C07K 14/35 (2006.01) C12N 9/88 (2006.01) C12N 9/90 (2006.01) C12N 15/61 (2006.01)

Patent

CA 2731547

The present invention is directed to a polypeptide which comprises: (i) an Rv2386c protein sequence; (ii) a variant of an Rv2386c protein sequence; or (iii) an immunogenic fragment of an Rv2386c protein sequence. In other aspects the invention is directed to associated polynucleotides, fusion proteins and methods for the treatment or prevention of tuberculosis.

La présente invention concerne un polypeptide qui comprend : (i) une séquence de la protéine Rv2386c; (ii) une variant d'une séquence de la protéine Rv2386c; ou (iii) un fragment immunogène d'une séquence de la protéine Rv2386c. Dans d'autres aspects, l'invention concerne des polynucléotides, protéines de fusion et procédés associés destinés au traitement ou à la prévention de la tuberculose.

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