The use of a protease or a protease inhibitor for the...

A - Human Necessities – 61 – K

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A61K 38/48 (2006.01) A61P 29/00 (2006.01) A61P 35/00 (2006.01) A61P 35/04 (2006.01) A61P 37/00 (2006.01)

Patent

CA 2586033

The invention relates the use of a cathepsin K inhibitor (CTKI) or CTK, a mutein, isoform, fused protein, functional derivative, active fraction, circularly permutated derivative, a salt or inducer thereof in the manufacture of a medicament for treating a disease in which SDF-1 activity and/or concentration is involved with the development and/or course of the disease.

Cette invention porte sur l'utilisation d'une cathepsine K (CTK) ou d'un inhibiteur de cathepsine K (CTKI), d'une mutéine, d'une isoforme, d'une protéine de fusion, d'un dérivé fonctionnel, d'une fraction active, d'un dérivé permuté circulairement, d'un sel ou d'un inducteur de ce dérivé pour la préparation d'un médicament destiné à traiter une maladie dans laquelle l'activité et ou la concentration du SDF-1 est associée au développement et/ou à l'évolution de la maladie.

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