A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/225 (2006.01)
Patent
CA 2283915
The use of one or several alkyl hydrogen fumarates of the general formula (see formula I) wherein R is a C1-5 alkyl, optionally in admixture with dialkyl fumarate of the formula (see formula II) and optionally customary pharmaceutical excipients and carriers for preparing a pharmaceutical composition in the form of micro-tablets or micro-pellets for treating psoriasis, psoriatic arthritis, neurodermatitis and enteritis regionalis Crohn.
L'invention concerne l'utilisation d'au moins un fumarate d'hydrogène d'alkyle de formule (I), dans laquelle R représente un alkyle C1-5, éventuellement mélangé avec du fumarate de dialkyle de formule (II), et éventuellement d'additifs et excipients pharmaceutiques usuels, pour produire une préparation pharmaceutique sous forme de microcomprimés ou micropastilles dans le but de traiter le psoriasis, la polyarthrite psoriasique, la névrodermite et l'entérite régionale.
Joshi Rajendra K.
Strebel Hans-Peter
Biogen Idec International Gmbh
Fumapharm Ag
Macrae & Co.
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