The use of anti biotics as vaccine adjuvants

Details The use of anti biotics as vaccine adjuvants The use of anti biotics as vaccine adjuvants

A - Human Necessities

61

K

A61K 39/39 (2006.01) A61P 31/04 (2006.01) A61P 37/04 (2006.01)

Patent

CA 2546195

The invention describes an adjuvant composition comprising an antimicrobial agent, in particular an azalide, wherein the antimicrobial agent acts as an adjuvant. More particularly, the adjuvant composition is a vaccine adjuvant. The invention further describes a vaccine comprising several components comprising (a) at least one antigen and (b) at least one antimicrobial agent, in particular an azalide, wherein the azalide acts as an adjuvant. An adjuvant composition or vaccine of the present invention is useful in the prevention and treatment of diseases caused by a pathogenic agent, a cancerous cell, or an allergen.

L'invention décrit une composition d'adjuvant qui comprend un agent antimicrobien, notamment un azalide, l'agent antimicrobien agissant comme un adjuvant. Plus spécifiquement, la composition d'adjuvant constitue un adjuvant de vaccins. L'invention décrit en outre un vaccin qui comprend des composants multiples, y compris (a) au moins un antigène et (b) au moins un agent antimicrobien, notamment un azalide qui agit comme un adjuvant. La composition d'adjuvant ou le vaccin décrits sont utiles pour prévenir et traiter des maladies causées par un agent pathogène, une cellule cancéreuse ou un allergène.

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