A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/4458 (2006.01) A61P 1/00 (2006.01) A61P 1/02 (2006.01) A61P 11/06 (2006.01) A61P 13/12 (2006.01) A61P 17/00 (2006.01) A61P 19/00 (2006.01) A61P 19/02 (2006.01) A61P 29/00 (2006.01) A61P 37/00 (2006.01)
Patent
CA 2646883
Compounds that may be used for the treatment or prevention of a condition associated with T-cell proliferation or that is mediated by pro-inflammatory cytokines are of formula (I): wherein at least one of R1 , R2 or R3 is not H and each is independently H, alkyl, CF3, CONH2, CN, halogen, NH2, NO2, NHCHO, NHCONH2, NHSO2alkyl, SOMe, SO2NH2, Salkyl, or CH2S02alkyl; and R4 is H or alkyl; or a salt thereof.
L'invention concerne des composés qui peuvent être employés dans le traitement prophylactique ou thérapeutique d'un état pathologique associé à la prolifération des cellules T, ou qui fait intervenir des cytokines proinflammatoires, et qui sont de formule (I) : où au moins l'un des groupements R1, R2 et R3 est différent de H, chacun représentant indépendamment H ou un groupement alkyle, CF3, CONH2, CN, halogéno, NH2, NO2, NHCHO, NHCONH2, NHSO2alkyle, SOMe, SO2NH2, Salkyle ou CH2SO2alkyle ; et R4 représente H ou un groupement alkyle ; ou un sel dudit composé.
Biocopea Limited
Sosei R&d Ltd.
Torys Llp
LandOfFree
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