The use of beta-aminoalcohols in the treatment of...

Details The use of beta-aminoalcohols in the treatment of... The use of beta-aminoalcohols in the treatment of...

A - Human Necessities

61

K

A61K 31/137 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2646882

A compound for therapeutic use, of the formula (I), wherein R1 is aryl or heteroaryl optionally substituted with R5; R2 is H, alkyl or CH2OH or forms part of a ring with R4; R3 is H, alkyl or CH2OH or forms part of a ring with R4; R4 is H, alkyl or (when forming part of a ring with R2 or R3) CH2; and R5 is alkyl, CF3, OH, Oalkyl, OCOalkyl, CONH2, CN, halogen, NH2, NO2, NHCHO, NHCONH2, NHSO2Me, CONH2, or SOMe; or a salt thereof.

La présente invention concerne un composé à applications thérapeutiques de formule (I), où R1 représente un groupement aryle ou hétéroaryle éventuellement substitué par R5 ; R2 représente H ou un groupement alkyle ou CH2OH, ou forme avec R4 une partie d'un cycle ; R3 représente H ou un groupement alkyle ou CH2OH, ou forme avec R4 une partie d'un cycle ; R4 représente H, un groupement alkyle ou, lorsqu'il forme une partie d'un cycle avec R2 ou R3, CH2 ; et R5 représente un groupement alkyle, CF3, OH, Oalkyle, OCOalkyle, CONH2, CN, halogéno, NH2, NO2, NHCHO, NHCONH2, NHSO2Me, CONH2 ou SOMe ; ou un sel dudit composé.

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